Assessment of biochemical changes in patients with type 2 diabetes mellitus along with urinary tract infection and their management on quality of life

Abstract

Objectives: Diabetes mellitus is a major endocrine disorder that affects the quality of life. The severity of the impact often depends on the presence of urinary tract infections (UTIs) in most patients with type 2 diabetes mellitus. It disrupts the physiological functioning of patients and also reduces their quality of life. Materials and Methods: The present study is designed to evaluate the biochemical changes in patients with diabetes, UTI, and diabetes with UTI. The study also evaluates the quality of life of these patients. The study included four groups of subjects: normal, diabetic, UTI, and diabetes with UTI, with 30 subjects in each group. Levels of hemoglobin, glucose, protein, urea, and creatinine were measured. Quality of life management was assessed using the Quality of Life (QOL) Index—Diabetes III Version. Results: The biochemical analysis showed a significant decrease in total protein, hemoglobin, and blood sugar levels in patients with diabetes and UTI compared to those without. A comparative study of the QOL Index revealed that health and functioning in daily life, socioeconomic status, psychological status, and family support are crucial for maintaining the QOL of individuals with diabetes, UTI, and both conditions combined, compared to those without these conditions. Conclusion: The overall results proved that the severity of diabetes and UTI is related to their quality of life.