TREGS SUPPRESS MACROPHAGE TUMORICIDAL FUNCTIONS

Authors

  • POULAMI SAHA Department of Zoology, Balurghat College, Balurghat, West Bengal
  • TATHAGATA CHAKRABORTY Department of Zoology, Balurghat College, Balurghat, West Bengal

DOI:

https://doi.org/10.55184/ijpas.v69i01.5

Keywords:

.

Abstract

Macrophages are well-known for their tumoricidal functions. In order to ascertain the effect of Regulatory T cells (Tregs) on macrophage tumoricidal functions, macrophages purified from healthy individuals were co-cultured with Tregs for 48 hours and cytotoxicity assay was performed with macrophage sensitive lymphoma cells, U937. Results clearly suggested that Tregs significantly inhibit (p less than) macrophage mediated tumor cell killing, as observed in cultures using different E:T ratios.

Downloads

Published

10-03-2015

How to Cite

SAHA, P., & CHAKRABORTY, T. (2015). TREGS SUPPRESS MACROPHAGE TUMORICIDAL FUNCTIONS. INDIAN JOURNAL OF PHYSIOLOGY AND ALLIED SCIENCES, 69(01), 21–27. https://doi.org/10.55184/ijpas.v69i01.5

Issue

Vol. 69 No. 01 (2015): INDIAN JOURNAL OF PHYSIOLOGY AND ALLIED SCIENCES

Section

Research Article