Hydroxymethyl ester derivative of hexadecanoic acid a possible hepatoprotectant from pulp of Cucurbita pepo

Abstract

It has been suggested that Cucurbita pepo, or pumpkin, is a veritable gold mine of fiber, polyunsaturated fatty acids, and antioxidants with a range of pharmacological properties, including hepatoprotective, anti-inflammatory, and antioxidant properties. The oxidative stress and liver damage may be lessened by the natural plant components present in pumpkin. The GC-MS analysis was aimed to determine the presence of any compound reported to be hepatoprotective or antioxidants from the pulp of C. pepo. The analysis was conducted using the aqueous fraction of hydroethanolic extract. The bioactive elements of the pulp of C. pepo extract were examined using a gas chromatography-mass spectrometer (GC-MS). The hexadecanoic acid, a reported hepatoprotectant and antioxidant effective against various diseases, was identified in the extract by GC-MS analysis. The hexadecanoic acid can be used in the possible medication and treatment for hepatic dysfunction. A wide range of illnesses can be treated with the many compounds discovered in plants employed in traditional medicine. Most people use traditional medicine based on compounds obtained from medicinal plants. Consequently, more study on these plants is required to comprehend their traits, efficacy, and safety. Therefore, the study will be connected to assess the C. pepo pulp extract’s ability to protect against hepatotoxicity.