URINARY PH AND INSULIN RESISTANCE IN OFFSPRING OF DIABETIC PARENTS

Abstract

Background and Aim: Recent studies try to find out parameters which can be used as predictors of type2 diabetes. Few investigations done in children of Type2 diabetic parents suggest the impact of family history and the presence of certain risk factors of the disease at an early age. We studied the presence of insulin resistance and changes in urinary pH in offspring of diabetic parents. Materials and Methods: Thirty subjects with one or both diabetic parents were compared with thirty subjects who are offspring of non diabetic parents. Results: No stastically significant difference was observed between the two groups in any of the values. Conclusion: Using insulin resistance and urinary pH as predictors of type2 diabetes is questionable. We may have to do further studies associating other risk factors like increased BMI with the family history.