Indian Journal of Physiology and Allied Sciences

piRNA diversity across model species and humans revealed through Kohonen maps

Authors : SAYAK GANGULI,
SAYAK GANGULI

DBT Centre for Bioinformatics, Presidency University, Kolkata.

ABHIJIT DATTA,
ABHIJIT DATTA

Department of Botany, Jhargram Raj College, Jhargram.

VINEET VISHAL,
VINEET VISHAL
(Corresponding Author)
vineet.vishal73@gmail.com

DBT Centre for Bioinformatics, Presidency University, Kolkata.

PANKAJ K. SINGH,
PANKAJ K. SINGH

DBT Centre for Bioinformatics, Presidency University, Kolkata.

ABHISEK R. BERA,
ABHISEK R. BERA

DBT Centre for Bioinformatics, Presidency University, Kolkata.

PROTIP BASU,
PROTIP BASU

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Address

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Address

Department of Botany, Jhargram Raj College, Jhargram.

Address

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Address

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Address

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Address

DBT Centre for Bioinformatics, Presidency University, Kolkata.

Page : 28-31 , vol : 69 ,No : 1 , Year : 2015

Abstract

Transposons (Transposable Elements or TEs) are a constant menace for human genome integrity as various diseases like SCID, DMD, Haemophilias, have been attributed to retrotransposon activity etc. Piwi-interacting RNA (piRNA) plays a pivotal role in RNA interference and their mechanism involved silencing selfish genetic material (Transposonable elements) in the germline and there by preserving genome integrity between generation. This study attempts to gain insights on the conserved features of piRNA using an artificial intelligence technique – Self Organizing Map (Kohonen Map).

Description

Research Article
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