Indian Journal of Physiology and Allied Sciences

Severe inflammation in oral planus might be responsible for carcinogenic potency

Authors : PRATITI GHOSH,
PRATITI GHOSH
(Corresponding Author)

Associate Professor & Head, Department of Physiology, West Bengal State University, Barasat, North 24 Parganas.

Address

Associate Professor & Head, Department of Physiology, West Bengal State University, Barasat, North 24 Parganas.

Page : 63-65 , vol : 69 ,No : 2 , Year : 2015

Abstract

The erosive form of oral lichen planus (OLP) shows apparently severe inflammation which is further confirmed from histological studies and from the overexpression of its inflammatory markers viz., NFkB, IL-6, TNF-a, COX-2 and iNOS. These characteristics in networked interaction with reactive oxygen or nitrogen species, inactivation of apoptosis or of death receptor pathways, as observed in cancerous condition, obviate OLP as a disease with tumorigenic potency.

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Review Article
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